COVID-19

[vnzla81]

Good video explaining some of the technology used for some of the vaccines.

[shags]

Update from Pfizer from the age groups 5 to 11. So a third of the dose gives similar antibody response in these age groups.



https://www.pfizer.com/news/press-re...opline-results

This, IMO, is really the key to getting back to normalcy. Great news.

[Gamble1]

Update from Pfizer from the age groups 5 to 11. So a third of the dose gives similar antibody response in these age groups.

The data summarized from this Phase 2/3 study, which is enrolling children 6 months to 11 years of age, was for 2,268 participants who were 5 to 11 years of age and received a 10 microgram dose level in a two-dose regimen. In the trial, the SARS-CoV-2–neutralizing antibody geometric mean titer (GMT) was 1,197.6 (95% confidence interval [CI, 1106.1, 1296.6]), demonstrating strong immune response in this cohort of children one month after the second dose. This compares well (was non-inferior) to the GMT of 1146.5 (95% CI: 1045.5, 1257.2) from participants ages 16 to 25 years old, used as the control group for this analysis and who were administered a two-dose regimen of 30 microgram.

https://www.pfizer.com/news/press-re...opline-results

[dal9]

[Gamble1]

FDA ignoring data about booster shots will end lovely I can already see it.

What do you mean?

[Motion Offense]

FDA ignoring data about booster shots will end lovely I can already see it.

[Gamble1]

It is pretty sobering news that 1 in 500 Americans have died of Covid.

[Gamble1]

So your saying I am COVID proof now....

Defiantly more covid proof than a person with a vaccine only. You basically have seen a third booster but it maybe better than a booster if the natural infection results in a more diverse antibody response. The key is whether that diversity adds up to protective antibodies that attack more than just the spike protein. In all likelihood it's a mixture of some that do and some that don't but the net effect is still probably better.

[graphic-er]

So here is a good paper on hybrid immunity which is the term used to describe someone who got covid then got the vaccine. The paper tries to explain why these people see a more robust immune response. This is also why some people are trying to mix and match vaccines but it is hard for me to believe this would mimic hybrid immunity especially if all the vaccines target one portion of the viral spike protein.

https://www.science.org/doi/full/10.1126/science.abj2258

So your saying I am COVID proof now....

[Gamble1]

So here is a good paper on hybrid immunity which is the term used to describe someone who got covid then got the vaccine. The paper tries to explain why these people see a more robust immune response. This is also why some people are trying to mix and match vaccines but it is hard for me to believe this would mimic hybrid immunity especially if all the vaccines target one portion of the viral spike protein.

https://www.science.org/doi/full/10.1126/science.abj2258

[Peck]

I don't know what "in system" means, but if it means hospitalized, that is wildly out of line with any other numbers reported; if so, may want to 2x check them.

Believe me we were as surprised as anyone when that number came out. These are ICU patients btw, that are located at the 3 campuses for that particular Hospital system. Why they have so many that have had the virus I do not know? As Gamble said sometimes things are counted oddly to say the least.

Now on a more personal note, my former partner on the Ambulance and my 23 year business partner until she retired last summer had to lay in an E.R. bed for 43 hours after suffering a heart attack because there were zero ICU beds available to her. We finally got her moved around 3 a.m. today.

[Gamble1]

I don't know what "in system" means, but if it means hospitalized, that is wildly out of line with any other numbers reported; if so, may want to 2x check them.

Not sure but there was a recent report about break through infections and hospilization numbers being inflated in the VA due to Covid not being the primary reason that people were hospitalized.

So if a vaccinated person goes in for a heart issue or diabetes and you test positive for covid then that gets counted in the records. When people pull the databases for large scale studies these are the type of things that can be misinterpreted. Most of these cases were people with a mild infection.

With what Peck posted I am not sure for what the disparity is but typically severe breakthrough infections are in the elderly 65 plus age group not in healthy middle age adults. This is supported by a recent Yale study that came out. In this study the median age for severe disease was 85.

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00558-2/fulltext

[Gamble1]

Not that health group. Think more along the east side of the city.

Gotcha and not surprising considering the trend. Hopefully this spikes is over soon.

[dal9]

Also 295 patients with Covid in system right now, 195 are not vaccinated 100 are. Not quite the % we were expecting.

I don't know what "in system" means, but if it means hospitalized, that is wildly out of line with any other numbers reported; if so, may want to 2x check them.

[Peck]

I thought they already made this announcement.

https://www.wane.com/news/indiana/iu...es-procedures/

https://www.ibj.com/articles/iu-heal...tive-surgeries

The vaccination rate at IU is above 97% which is good news.

Not that health group. Think more along the east side of the city.