(1-0) The Giants handled the Panthers last week, 31-18, and hope to jump on the Colts while they are down. QB Eli Manning will be more than motivated to even the series 1-1 against older brother, Peyton.
(0-1) After suffering a beat down from division-rival Houston last week, the Colts hope to rebound with a win in the second, "Manning Bowl."
Time: 8:20 PM ET
Location: Lucas Oil Stadium, Indianapolis, IN